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Graphical abstract template · Multipanel figures · Worked examples

Four-panel figure: tumour growth and survival in vivo

An in vivo efficacy figure: the dosing schedule on a timeline, tumour volume over time for three groups (mean ± SEM), Kaplan–Meier survival with a log-rank test, and body weight as a measure of tolerability.

Updated 2 cited papers46 editable layers

Four-panel figure: tumour growth and survival in vivo: preview of the editable figure template
Preview at reduced size. The full figure opens in the editor, where every layer can be changed.

At a glance

Category
Multipanel figures
Method
Worked examples
Product
A 2 × 2 figure (a–d) for a preclinical efficacy study
Key result
Example data (exponential growth with treatment effects, exponential survival times); not from a study
Figure
691.65 × 373.54 px (16:9), 46 editable layers, 3 generated objects

Step by step

  1. a · ScheduleTumour implantation, randomisation and dosing days on one timeline
  2. b · Tumour volumeMean ± SEM per group over time
  3. c · SurvivalKaplan–Meier curves with censor ticks and a log-rank test, computed in the graph
  4. d · Body weightChange from day 0, a quick read of tolerability

Strengths

  • The panels reviewers look for in an efficacy study
  • Survival statistics computed from the table

Limitations

  • Example values only

Uses

  • Cancer nanomedicine and drug papers
  • Grant figures

Papers this template follows

  1. Weissgerber, Milic, Winham & Garovic, “Beyond bar and line graphs: time for a new data presentation paradigm”, PLoS Biol. 2015. doi:10.1371/journal.pbio.1002128review
  2. Rougier, Droettboom & Bourne, “Ten simple rules for better figures”, PLoS Comput. Biol. 2014. doi:10.1371/journal.pcbi.1003833review

Example data generated for this template. Replace it with your own.

How templates are written and checked: editorial guidelines.

Questions

What does the “Four-panel figure: tumour growth and survival in vivo” template show?

An in vivo efficacy figure: the dosing schedule on a timeline, tumour volume over time for three groups (mean ± SEM), Kaplan–Meier survival with a log-rank test, and body weight as a measure of tolerability.

What are the steps shown in “Four-panel figure: tumour growth and survival in vivo”?

1. a · Schedule: Tumour implantation, randomisation and dosing days on one timeline. 2. b · Tumour volume: Mean ± SEM per group over time. 3. c · Survival: Kaplan–Meier curves with censor ticks and a log-rank test, computed in the graph. 4. d · Body weight: Change from day 0, a quick read of tolerability.

Which papers is “Four-panel figure: tumour growth and survival in vivo” based on?

Weissgerber, Milic, Winham & Garovic, “Beyond bar and line graphs: time for a new data presentation paradigm”, PLoS Biol. 2015 (doi:10.1371/journal.pbio.1002128); Rougier, Droettboom & Bourne, “Ten simple rules for better figures”, PLoS Comput. Biol. 2014 (doi:10.1371/journal.pcbi.1003833).

Can I edit the “Four-panel figure: tumour growth and survival in vivo” template?

Yes. Open it in the LabCanvas editor: all 46 layers are editable, including 3 generated objects (structures, plots, equipment) with their own settings. Change the text, colours and layout, then export PNG, TIFF, SVG or PDF.

Do I need an account to use this template?

Not to view it here. To open and edit it, sign in to LabCanvas or create a free account (the free plan keeps up to 3 designs). Downloading the figure is part of LabCanvas Pro (US$19 a month or US$199 a year).

multipanel figurein vivotumour growthxenograftKaplan-Meiersurvival curvelog-rank testbody weightdosing schedulepreclinical studynanomedicinejournal figure

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